This case-control study assesses relations of human papillomavirus (HPV) type 16 infection, sexual history, cigarette smoking, and oral contraceptive use to low-and high-grade cervical intraepithelial neoplasia (CIN).
A total of 548 high-grade and 338 low-grade CIN cases and 612 controls were identified among women seen at a colposcopy clinic in Quebec, Quebec, Canada, in 1988-1989.
Interviews, colposcopy, cervical scrapings, and colposcopically directed biopsies were performed.
One pathologist reviewed all histologic slides.
Southern blot techniques were used to assay specimens for HPV 16 DNA.
Lifetime number of sexual partners was related to low-and high-grade CIN.
Mots-clés Pascal : Tumeur maligne, Col utérus, Epidémiologie, Facteur risque, Femme, Homme, Québec, Canada, Amérique du Nord, Amérique, Contraception, Voie orale, Papillomavirus, Papovaviridae, Virus, Tabagisme
Mots-clés Pascal anglais : Malignant tumor, Uterine cervix, Epidemiology, Risk factor, Woman, Human, Quebec, Canada, North America, America, Contraception, Oral administration, Papillomavirus, Papovaviridae, Virus, Tobacco smoking
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0016890
Code Inist : 002B20C02. Création : 09/06/1995.