Following vaccination of children using high-titre live measles vaccine, excess non-specific mortality was reported, particularly among females.
Since vaccination with live measles virus results in a temporary depression of the immune response to other antigens, the female predominance in subsequent non-measles mortality may be due to sex differences in response to live measles vaccines.
In this study, the immunogenicity of standard titre live Schwarz strain measles vaccine was examined 2 and 4 weeks post-vaccination in 223 males and 66 female aged 18-20 years in Israel in 1991.
Females had higher post-vaccination geometric mean titre (GMT) at all levels of pre-vaccination titres at both 2 and 4 weeks.
Mots-clés Pascal : Rougeole, Virose, Infection, Vaccination, Prévention, Adulte jeune, Homme, Réponse immune, Immunité humorale, Sexe, Israël, Asie
Mots-clés Pascal anglais : Measles, Viral disease, Infection, Vaccination, Prevention, Young adult, Human, Immune response, Humoral immunity, Sex, Israel, Asia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0000615
Code Inist : 002B05C02C. Création : 09/06/1995.