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  1. Sex differences in the humoral antibody response to liver measles vaccine in young adults.

    Article - En anglais

    Background

    Following vaccination of children using high-titre live measles vaccine, excess non-specific mortality was reported, particularly among females.

    Since vaccination with live measles virus results in a temporary depression of the immune response to other antigens, the female predominance in subsequent non-measles mortality may be due to sex differences in response to live measles vaccines.

    Methods

    In this study, the immunogenicity of standard titre live Schwarz strain measles vaccine was examined 2 and 4 weeks post-vaccination in 223 males and 66 female aged 18-20 years in Israel in 1991.

    Results

    Females had higher post-vaccination geometric mean titre (GMT) at all levels of pre-vaccination titres at both 2 and 4 weeks.

    Mots-clés Pascal : Rougeole, Virose, Infection, Vaccination, Prévention, Adulte jeune, Homme, Réponse immune, Immunité humorale, Sexe, Israël, Asie

    Mots-clés Pascal anglais : Measles, Viral disease, Infection, Vaccination, Prevention, Young adult, Human, Immune response, Humoral immunity, Sex, Israel, Asia

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0000615

    Code Inist : 002B05C02C. Création : 09/06/1995.