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  1. Immunization of 6 and 9 month old infants with AIK-C, Edmonston-Zagreb, Leningrad-16 and Schwarz strains of measles vaccine.

    Article - En anglais

    Background

    Measles kills more than 1 million infants per year and is particularly lethal in infants<1 year old in developing countries.

    Recent reports have suggested that measles vaccines of different strains and titre differ in their immunogenicity in young infants.

    We sought to identify strains and titres of measles vaccines which would be effective in 6 and 9 month old infants.

    Methods

    We conducted a randomized trial of AIK-C, Edmonston-Zagreb (EZ), Leningrad-16 and Schwarz strains of measles vaccine at different titres in 1202 6 month old and 1250 9 month old infants.

    Antibody levels were measured by haemagglutination inhibition assay.

    Mots-clés Pascal : Rougeole, Virose, Infection, Nourrisson, Homme, Vaccination, Prévention, Etude comparative, Vaccin, Souche, Efficacité, Age, Uzbekistan

    Mots-clés Pascal anglais : Measles, Viral disease, Infection, Infant, Human, Vaccination, Prevention, Comparative study, Vaccine, Strain, Efficiency, Age

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0000614

    Code Inist : 002B05C02C. Création : 09/06/1995.