Measles kills more than 1 million infants per year and is particularly lethal in infants<1 year old in developing countries.
Recent reports have suggested that measles vaccines of different strains and titre differ in their immunogenicity in young infants.
We sought to identify strains and titres of measles vaccines which would be effective in 6 and 9 month old infants.
We conducted a randomized trial of AIK-C, Edmonston-Zagreb (EZ), Leningrad-16 and Schwarz strains of measles vaccine at different titres in 1202 6 month old and 1250 9 month old infants.
Antibody levels were measured by haemagglutination inhibition assay.
Mots-clés Pascal : Rougeole, Virose, Infection, Nourrisson, Homme, Vaccination, Prévention, Etude comparative, Vaccin, Souche, Efficacité, Age, Uzbekistan
Mots-clés Pascal anglais : Measles, Viral disease, Infection, Infant, Human, Vaccination, Prevention, Comparative study, Vaccine, Strain, Efficiency, Age
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0000614
Code Inist : 002B05C02C. Création : 09/06/1995.