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  1. Screening for hemochromatosis : a cost-effectiveness study based on 12,258 patients.

    Article - En anglais

    Background/Aims 

    Current emphasis in hemochromatosis has focused on early detection and treatment to prevent permanent liver damage and hepatocellular carcinoma.

    Thus far, only normal population and highrisk groups have been screened but not patients seeking medical care.

    Methods 

    Serum iron levels were determined in consecutive fasting blood samples collected in the morning from 12,258 Mayo Clinic patients.

    Results 

    One hundred twenty-seven patients had an initial serum iron concentration =180 mug/dL.

    Eight patients (age, 38-71 years ; 7 men and 1 woman) had transferrin saturation =62% (range, 84-99) and serum ferritin value =400 mug/L (range, 457-4004) with no other explanation for the abnormal iron test results.

    Mots-clés Pascal : Hémochromatose, Economie, Coût, Epidémiologie, Homme, Homozygotie, Hétérozygotie, Prévention, Complication, Pigment, Fer, Analyse quantitative, Plasma sanguin, Métabolisme pathologie, Enzymopathie

    Mots-clés Pascal anglais : Hemochromatosis, Economy, Costs, Epidemiology, Human, Homozygozity, Heterozygozity, Prevention, Complication, Pigments, Iron, Quantitative analysis, Blood plasma, Metabolic diseases, Enzymopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0714708

    Code Inist : 002B30A03B. Création : 09/06/1995.