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  1. 766 cases of oral cleft in Italy : data from Emilia Romagna (IMER) and northeast Italy (NEI) registers.

    Article - En anglais

    Epidemiological and genetic variables for oral clefts were analysed for the years 1981-1989 in a case-control study of congenital malformations in the Emilia Romagna, Veneto, and Friuli regions, and in the Trento and Bolzano hospitals.

    Birth prevalence for all cases of cleft lip with or without cleft palate (CL (P)) was 8.2 per 10,000 births, and that for cleft palate only (CP) was 6.1 per 10,000.

    Coexisting abnormalities were found in 23% of CL (P) cases and in 43% of CP.

    No clusters in time or space were detected.

    For isolated clefts, a predominance of males among CL (P) and of females among CP was found ; epilepsy was the only maternal risk factor correlated with clefts, and an association between clefting and consanguinity was found.

    Mots-clés Pascal : Bec de lièvre, Fissure congénitale, Palais, Epidémiologie, Déterminisme génétique, Registre, Nouveau né, Homme, Prévalence, Etude familiale, Italie, Europe, Malformation, Stomatologie

    Mots-clés Pascal anglais : Cleft lip, Cleft, Palate, Epidemiology, Genetic inheritance, Register, Newborn, Human, Prevalence, Family study, Italy, Europe, Malformation, Stomatology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0684072

    Code Inist : 002B10C02. Création : 09/06/1995.