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  1. Familial aggregation of lens opacities : the Framingham eye study and the Framingham offspring eye study.

    Article - En anglais

    Eye examination data from 1,086 parents examined in the Framingham Eye Study (1973-1975) and 896 offspring examined in the Framingham Offspring Eye Study (1989-1991) were used to study familial associations for nuclear, cortical, and posterior subcapsular lens opacities.

    Associations between spouses, between parents and offspring, and between siblings were explored.

    The generalized estimating equations (GEE2) approach to logistic regression was used to simultaneously model risk of lens opacity and familial associations.

    Specifically, this provided odds ratios, adjusted for age (the age range was 50-74 years) and sex, for the familial associations.

    Mots-clés Pascal : Cataracte, Epidémiologie, Parent, Descendance, Etude familiale, Déterminisme génétique, Age, Modèle statistique, Etats Unis, Amérique du Nord, Amérique, Oeil pathologie, Cristallin pathologie, Segment antérieur pathologie

    Mots-clés Pascal anglais : Cataract, Epidemiology, Parent, Progeny, Family study, Genetic inheritance, Age, Statistical model, United States, North America, America, Eye disease, Lens disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0684060

    Code Inist : 002B09G. Création : 09/06/1995.