To estimate the presence of, and the risk factors for HTLV-I and HTLV-II infections among HIV-1 infected subjects in Sao Paulo, Brazil, a serosurvey was performed in 471 HIV-1 infected patients, including 216 intravenous drug addicts (IVDA), 229 homosexual/bisexual men, and 26 with other risk factors.
Serum samples were screened for HTLV seroreactivity by ELISA ; reactive samples were analyzed by Western Blot (WB), using whole HTLV-I lysate as antigen.
To confirm and discriminate HTLV-I and HTLV-II infections, sera presenting any bands on WB were further analyzed by a WB containing recombinant HTLV-I and HTLV-II proteins (WB 2.3), and by enzyme immunoassays using synthetic peptides specific for envelope proteins (Synth-EIA).
Mots-clés Pascal : SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Association, Virus HTLV1, Virus HTLV2, Epidémiologie, Prévalence, Sérologie, Homme, Brésil, Amérique du Sud, Amérique, Réaction chaîne polymérase, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Association, HTLV-I virus, HTLV-II virus, Epidemiology, Prevalence, Serology, Human, Brazil, South America, America, Polymerase chain reaction, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0682337
Code Inist : 002B06D01. Création : 09/06/1995.