Effect of incomplete exposure assessment on epidemiologic dose-response analyses.
When potentially hazardous agents have multiple environmental sources, failure to include all exposure sources can constitute a type of measurement error.
In addition, the effects of exposure from one source can also be confounded by exposure to other sources of the same agent.
In this study clarification of these concepts is sought, and the direction and magnitude of the resulting bias in epidemiologic measures of association are examined.
METHODS The bias in dose-response functions when the exposure data omit some sources of the agent was estimated with linear and log-linear models to compute risk differences and risk ratios under different assumptions about the magnitude and correlation of exposures from measured and unmeasured sources.
Mots-clés Pascal : Epidémiologie, Méthodologie, Evaluation, Exposition, Classification, Erreur mesure, Relation dose réponse, Biais
Mots-clés Pascal anglais : Epidemiology, Methodology, Evaluation, Exposure, Classification, Measurement error, Dose activity relation, Bias
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0680180
Code Inist : 002B30A01A1. Création : 09/06/1995.