Several outbreaks of multidrug resistant tuberculosis (MDR-TB) have recently occurred in which healthcare workers and others have become infected.
Given the lack of clinical data to guide preventive therapy for such contacts, a Delphi survey of a panel of 31 TB therapy experts was undertaken to identify a consensus regimen.
An initial questionnaire presented three scenarios describing persons with significant exposure to MDR-TB and with new tuberculin skin test reactions>15 mm (except one anergic patient) without evidence of disease.
Panelists were asked to suggest possible preventive therapy regimens.
Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Poumon, Résistance traitement, Pyrazinamide, Ciprofloxacine, Association médicamenteuse, Prévention, Traitement, Homme, Transmission homme homme, Appareil respiratoire pathologie, Poumon pathologie, Antituberculeux, Chimiothérapie
Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Lung, Negative therapeutic reaction, Drug combination, Prevention, Treatment, Human, Transmission from man to man, Respiratory disease, Lung disease, Antituberculous agent, Chemotherapy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0671805
Code Inist : 002B02S02. Création : 09/06/1995.