First-and second-degree relatives of an unselected series of 402 breast cancer patients have been studied for their cancer experience.
In the first-degree relatives an excess of all cancers is seen [overall relative risk (RR)=1.28, P=0.002 ; males RR=1.26, P=0.047 ; females RR=1.30, P=0.022).
There is a marked excess of sarcoma (RR=4.26, P=0.0064) ; females are at high risk of breast cancer (RR=2.68, P<0.0001) and males have an excess of carcinoma of the lip, oral cavity and pharynx (RR=4.22, P=0.0032).
Second-degree relatives have a non-significant excess of all cancers (RR=1.14, P=0.14) ; females have a borderline excess of breast cancer (RR=1.53, P=0.08) and an excess of carcinoma of the kidney (RR=7.46, P=0.0012) and males have an excess of carcinoma of the trachea and lung (RR=1.50, PP=0.032).
Mots-clés Pascal : Epithélioma, Glande mammaire, Tumeur maligne, Facteur risque, Incidence, Epidémiologie, Angleterre, Grande Bretagne, Royaume Uni, Europe, Parent, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Carcinoma, Mammary gland, Malignant tumor, Risk factor, Incidence, Epidemiology, England, Great Britain, United Kingdom, Europe, Parent, Human, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0662382
Code Inist : 002B04B. Création : 09/06/1995.