We analyzed the mortality rates of amyotrophic lateral sclerosis (ALS) in Italy from 1958 to 1987.
The overall mean annual mortality rate, adjusted to the 1981 Italian population, was 0.68/100,000 (95% confidence interval, 0.64 to 0.72) ; 0.86 for men ; and 0.62 for women.
During that period, mortality increased for both sexes : from 1958/1962 to 1983/1987, mortality increased by 60% for women and 24% for men.
The slope for women was 0.07, and for men, 0.02.
Moreover, the mortality rate increased in older age groups and was stable for subjects under 45 years old.
There was no clear birth-cohort effect, but in any cohort the age-specific mortality rate increased with advancing age, with no decline for the oldest age.
Mots-clés Pascal : Sclérose latérale amyotrophique, Mortalité, Italie, Europe, Etude cohorte, Epidémiologie, Homme, Système nerveux pathologie, Système nerveux central pathologie, Moelle épinière pathologie, Maladie dégénérative
Mots-clés Pascal anglais : Amyotrophic lateral sclerosis, Mortality, Italy, Europe, Cohort study, Epidemiology, Human, Nervous system diseases, Central nervous system disease, Spinal cord disease, Degenerative disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0662011
Code Inist : 002B17G. Création : 09/06/1995.