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  1. An investigation of gene-environment interaction in the etiology of rheumatoid arthritis.

    Article - En anglais

    The etiology of rheumatoid arthritis is explained by both genetic and hormonal environment factors.

    Using a survey of twins conducted in the British Isles in 1989, the authors have investigated the extent of a possible genetic-hormonal environment interaction in conferring susceptibility for rheumatoid arthritis.

    This was done by comparing the hormonal history of three groups of cases and controls : 1) disease-discordant monozygotic twins, thus matching cases and controls for genetic susceptibility ; 2) disease-discordant dizygotic twins ; and 3) a group of twins with rheumatoid arthritis who were age matched to population controls.

    Mots-clés Pascal : Polyarthrite rhumatoïde, Etiologie, Jumeau, Homme, Déterminisme génétique, Hormone, Royaume Uni, Europe, Epidémiologie, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune

    Mots-clés Pascal anglais : Rheumatoid arthritis, Etiology, Twin, Human, Genetic inheritance, Hormone, United Kingdom, Europe, Epidemiology, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0647077

    Code Inist : 002B15D. Création : 09/06/1995.