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  1. Pulmonary function decline and a 17-year total mortality : the Honolulu heart program.

    Article - En anglais

    The Honolulu Heart Program continues to follow a cohort of Japanese-American men initially aged 45-68 years, of whom 4,000 had three acceptable measurements of forced expiratory volume in 1 second (FEV1) between 1965 and 1974 and were free of cardiovascular disease and cancer.

    The 6-year rate of change (slope) in FEV1 was calculated using a within-person linear regression method.

    Men were divided into tertiles based on the rate of change in FEV1.

    During 17 subsequent years of follow-up, 796 deaths occurred.

    The tertile with the greatest rate of decline in FEV1 (mean, - 61 ml/year) had the highest age-adjusted total mortality rate (17.3/1,000 person-years), followed by rates of 13.2 for the middle tertile (mean, - 25 ml/year) and 11.0 for men with the smallest change in FEV1 (mean, 9 ml/year) (test for trend, p<0.0001).

    Mots-clés Pascal : Mortalité, Fonction respiratoire, Japonais, Hawaï, Homme, Etude longitudinale, Epidémiologie, Tabagisme, Appareil respiratoire, Poumon, Polynésie, Océanie

    Mots-clés Pascal anglais : Mortality, Lung function, Japanese, Hawaii, Human, Follow up study, Epidemiology, Tobacco smoking, Respiratory system, Lung, Polynesia, Oceania

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0647072

    Code Inist : 002B30A01A2. Création : 09/06/1995.