The aim of the study was to investigate the asbestos-associated risk of lung cancer according to histological type of cancer, lobe of origin, pulmonary concentration, and type of amphibole fibers and also to estimate the etiologic fraction of asbestos for lung cancer.
The pulmonary concentration of asbestos fibers in 113 surgically treated male lung cancer patients and 297 autopsy cases among men serving as referents was determined by scanning electron microscopy.
The age-and smoking-adjusted odds ratios of lung cancer were calculated according to pulmonary fiber concentration for all lung cancer types, sqaumous-cell carcinoma, and adenocarcinoma and for the lower-lobe and the upper-and middle-lobe cancers.
Mots-clés Pascal : Amiante, Carcinogène, Exposition professionnelle, Tumeur maligne, Bronchopulmonaire, Homme, Toxicité, Epidémiologie, Localisation, Médecine travail, Finlande, Europe, Crocidolite, Fibre minérale, Appareil respiratoire pathologie, Poumon pathologie, Amosite, Anthophyllite, Type histologique
Mots-clés Pascal anglais : Asbestos, Carcinogen, Occupational exposure, Malignant tumor, Bronchopulmonary, Human, Toxicity, Epidemiology, Localization, Occupational medicine, Finland, Europe, Mineral fiber, Respiratory disease, Lung disease, Histological type
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0634786
Code Inist : 002B11A. Création : 09/06/1995.