This study examined whether inter-observer variability in rating tumor characteristics affected results of an investigation of surveillance bias and malignant melanoma at the Lawrence Livermore National Laboratory.
The 20 cases from the Laboratory and their 36 non-Laboratory controls belonged to the same pre-paid health plan and were diagnosed with melanoma between 1970 and 1984.
Tumors were independently and then jointly rated by three dermatopathologists blind to the subjects'Laboratory status.
The mean difference between the reviewers and the consensus reading for tumor thickness was small, ranging from - 0.06mm (95% confidence interval [CI]-0.12,0.00) to 0.00 mm (95% CI-0.07,0.07).
Agreement was much lower for histologic type (kappa=0.48,95% CI 0.37,0.58).
Mots-clés Pascal : Epidémiologie, Méthodologie, Mélanome malin, Surveillance sanitaire, Homme, Variabilité, Observateur, Interprétation, Histopathologie, Biais, Tumeur maligne
Mots-clés Pascal anglais : Epidemiology, Methodology, Malignant melanoma, Sanitary surveillance, Human, Variability, Observer, Interpretation, Histopathology, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0633264
Code Inist : 002B30A01A1. Création : 09/06/1995.