A clinic-based case-control study was conducted to determine the association between vitamin supplement use and risk of basal cell carcinoma (BCC) of the skin.
The subjects were 131 patients with histopathologically confirmed primary BCC and 200 cancer-free controls with non-premalignant skin disorders.
Use of any vitamins (mainly multivitamins and vitamins A, C, and E) was associated with reduced risk of BCC.
After controlling for age, sex, cigarette smoking, number of lifetime severe sunburns, and skin actinic elastosis, regular vitamin supplementation was associated with a significantly reduced risk of BCC (odds ratio (OR)=0.3. ; 95% confidence interval (CI)=0.2-0.6).
Mots-clés Pascal : Epithélioma basocellulaire, Prévention, Epidémiologie, Homme, Régime alimentaire enrichi, Vitamine, Etats Unis, Amérique du Nord, Amérique, Peau pathologie, Tumeur maligne, Etude cas témoin
Mots-clés Pascal anglais : Basal cell carcinoma, Prevention, Epidemiology, Human, Supplemented diet, Vitamin, United States, North America, America, Skin disease, Malignant tumor, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0633256
Code Inist : 002B08A. Création : 09/06/1995.