Results of clinical and epidemiologic studies have shown an increased risk for neural tube defects (NTD) in infants whose mothers were exposed to heat during pregnancy.
However, the risk for NTD in infants whose mothers had influenza during pregnancy has not been well studied.
This population-based case-control study of infants born in metropolitan Atlanta, Georgia, from 1968 through 1980 included 385 infants with NTD, 3,647 infants with other birth defects, and 2,676 infants without birth defects.
Of the 385 mothers of case infants, 31 reported having a 2-day or longer episode of flu with fever from 1 month before through 3 months after conception (odds ratio (OR)=3.0 ; 95% confidence interval (CI) 1.9-4.7).
Mots-clés Pascal : Malformation, Tube neural, Nourrisson, Homme, Epidémiologie, Grippe, Virose, Infection, Fièvre, Mère, Gestation, Géorgie, Etats Unis, Amérique du Nord, Amérique, Système nerveux pathologie, Système nerveux central pathologie
Mots-clés Pascal anglais : Malformation, Neural tube, Infant, Human, Epidemiology, Influenza, Viral disease, Infection, Fever, Mother, Pregnancy, Georgia, United States, North America, America, Nervous system diseases, Central nervous system disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0624942
Code Inist : 002B17D. Création : 09/06/1995.