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  1. Theoretical epidemiologic and morbidity effects of routine varicella immunization of preschool children in the United States.

    Article - En anglais

    The authors studied the effects of routine varicella immunization of US preschool children and of implementation of a catch-up program in older children on the age distribution of cases and on overall morbidity, with emphasis on the sensitivity of the results to level of vaccine coverage, duration of protection, responsiveness to boosting, relative residual susceptibility and infectiousness, and degree of morbidity among vaccine breakthrough cases.

    An age-structured theoretical transmission model was used, with values for vaccine efficacy based on a review of the literature by an expert panel.

    Mots-clés Pascal : Varicelle, Virose, Infection, Vaccination, Prévention, Enfant, Homme, Age préscolaire, Modèle mathématique, Efficacité, Evaluation, Epidémiologie, Morbidité, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Varicella, Viral disease, Infection, Vaccination, Prevention, Child, Human, Preschool age, Mathematical model, Efficiency, Evaluation, Epidemiology, Morbidity, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0622889

    Code Inist : 002B05C02B. Création : 09/06/1995.