In previous decades, infants who received blood transfusions shortly after birth or in utero might have been infected at a particularly vulnerable age by some blood-borne oncogenic virus.
A cohort of such infants has therefore been followed into adult life to see if they suffered any excess of neoplastic disease or of non-neoplastic mortality.
A total of 12,690 infants were identified who were transfused between 1 January 1942 and 31 December 1970, in most cases for the prevention or treatment of haemolytic disease of the newborn.
All but 361 (2.8%) were found to have been registered with a National Health Sewice (NHS) practitioner and were followed in the NlHS central records until they died, emigrated, were removed from NHS lists or until 1 January 1992, whichever occurred first.
Mots-clés Pascal : Tumeur maligne, Lymphome non hodgkinien, Leucémie, Facteur risque, Epidémiologie, Royaume Uni, Europe, Virus oncogène, Transfusion, Sang, Etude cohorte, Adulte, Homme, Hémopathie maligne, Lymphoprolifératif syndrome, Enfance
Mots-clés Pascal anglais : Malignant tumor, Non Hodgkin lymphoma, Leukemia, Risk factor, Epidemiology, United Kingdom, Europe, Oncogenic virus, Transfusion, Blood, Cohort study, Adult, Human, Malignant hemopathy, Lymphoproliferative syndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0605573
Code Inist : 002B04B. Création : 09/06/1995.