Smoking and drinking habits as well as family history were examined in 143 men with esophageal cancer, including 30 who had associated second cancers of the upper aerodigestive tract (UADT) and 113 who did not.
The risk of second cancers of UADT associated with the main lesions of the esophagus was evaluated, using odds ratios (ORs).
As a result, the ORs of second cancers for current smoking and drinking were 5. J and 7.6 respectively.
The ORs significantly increased to 12.7 and 14.7 in heavy smokers and in heavy drinkers respectively.
Furthermore, the risk of second cancer also significantly increased (8-fold) in patients who had close relatives with UADT cancer, compared to those without family history of any cancer.
Mots-clés Pascal : Tumeur maligne, Oesophage, Association, Epithélioma, Voie aérodigestive supérieure, Second cancer, Facteur risque, Alcoolisme, Tabagisme, Histoire familiale, Antécédent, Epidémiologie, Japon, Asie, Homme, Oesophage pathologie, Appareil digestif pathologie, ORL pathologie
Mots-clés Pascal anglais : Malignant tumor, Esophagus, Association, Carcinoma, Upper aerodigestive tract, Second cancer, Risk factor, Alcoholism, Tobacco smoking, Family story, Antecedent, Epidemiology, Japan, Asia, Human, Esophageal disease, Digestive diseases, ENT disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0591791
Code Inist : 002B10B01. Création : 09/06/1995.