In a large urban centre of a developed nation, 63 household contacts of 20 index cases with acute hepatitis A virus infection and 95 household contacts of 29 index cases with acute hepatitis B virus infection were prospectively followed for 2 years to document the risk of acquiring acute hepatitis from the index case.
Twenty-one of 63 (33%) hepatitis A virus household contacts had serologic evidence of previous hepatitis A virus infection on the initial serum sample.
Of the remaining 42 susceptible individuals, 22 (52%) were or became IgM anti-HAV positive within 6 months of the diagnosis in the index case.
With respect to hepatitis B virus infection, 18/95 (11%) household contacts had serologic evidence of previous hepatitis B virus infection on the initial serum sample.
Mots-clés Pascal : Hépatite virale A, Virose, Infection, Aigu, Virus hépatite B, Hepadnaviridae, Virus, Homme, Transmission homme homme, Epidémiologie, Milieu urbain, Immunoprophylaxie, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis A, Viral disease, Infection, Acute, Hepatitis B virus, Hepadnaviridae, Virus, Human, Transmission from man to man, Epidemiology, Urban environment, Immunoprophylaxis, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0588233
Code Inist : 002B13C03. Création : 09/06/1995.