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  1. Pertussis in Massachusetts, 1981-1991 : incidence, serologic diagnosis, and vaccine ffectiveness.

    Article - En anglais

    Massachusetts provides diphtheria-tetanus toxoid-pertussis (DTP) vaccine, and since 1980 has monitored pertussis with a statewide diagnostic service.

    The incidence of bacteriologically con6rmed pertussis was 104.5 per 100,000 person-years in 1-month-old infants and declined progressively thereafter.

    Infants<6 months old experienced disproportionate morbidity : 44% of bacteriologically confirmed pertussis, 64% of hospitalizations, and 71% of hospital days.

    Most children with pertussis had received<3 DTP doses during childhood, whereas 87% of adolescents with pertussis had received =4 doses.

    Serodiagnosis by single serum anti-pertussis toxin antibody ELISA increased the incidence of confirmed pertussis in persons 11-19 years old from 3.0 to 12.9 per 100,000 and in persons =20 years old from 0.16 to 0.56 per 100,000.

    Mots-clés Pascal : Coqueluche, Bactériose, Infection, Anticorps, Sérum, Exploration immunologique, Epidémiologie, Vaccination, Immunoprophylaxie, Massachusetts, Etats Unis, Amérique du Nord, Amérique, Incidence, Diagnostic, Homme

    Mots-clés Pascal anglais : Whooping cough, Bacteriosis, Infection, Antibody, Serum, Immunological investigation, Epidemiology, Vaccination, Immunoprophylaxis, Massachusetts, United States, North America, America, Incidence, Diagnosis, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0581140

    Code Inist : 002B05C02C. Création : 09/06/1995.