Pertussis in Massachusetts, 1981-1991 : incidence, serologic diagnosis, and vaccine ffectiveness.
Massachusetts provides diphtheria-tetanus toxoid-pertussis (DTP) vaccine, and since 1980 has monitored pertussis with a statewide diagnostic service.
The incidence of bacteriologically con6rmed pertussis was 104.5 per 100,000 person-years in 1-month-old infants and declined progressively thereafter.
Infants<6 months old experienced disproportionate morbidity : 44% of bacteriologically confirmed pertussis, 64% of hospitalizations, and 71% of hospital days.
Most children with pertussis had received<3 DTP doses during childhood, whereas 87% of adolescents with pertussis had received =4 doses.
Serodiagnosis by single serum anti-pertussis toxin antibody ELISA increased the incidence of confirmed pertussis in persons 11-19 years old from 3.0 to 12.9 per 100,000 and in persons =20 years old from 0.16 to 0.56 per 100,000.
Mots-clés Pascal : Coqueluche, Bactériose, Infection, Anticorps, Sérum, Exploration immunologique, Epidémiologie, Vaccination, Immunoprophylaxie, Massachusetts, Etats Unis, Amérique du Nord, Amérique, Incidence, Diagnostic, Homme
Mots-clés Pascal anglais : Whooping cough, Bacteriosis, Infection, Antibody, Serum, Immunological investigation, Epidemiology, Vaccination, Immunoprophylaxis, Massachusetts, United States, North America, America, Incidence, Diagnosis, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0581140
Code Inist : 002B05C02C. Création : 09/06/1995.