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  1. A seroepidemiological study of human immunodeficiency virus infection in Northeast Zaire.

    Article - En anglais

    To evaluate the incidence of human immunodeficiency virus type 2 infections in an endemic African area, we have studied 134 patients from Northeast Zaire.

    Sera were tested For.

    HIV-1 and HIV-2 antibodies to asses cross-reactivity or a possible double infection.

    Sixty five (48.5%) serum samples were reactive For HIV-1 and six (4.5%) For HIV-2 using specific Western blots.

    The enzyme immunoassays used to detect HIV-2 showed cross-reactivity with HIV-1 in 17 samples (16.5%). Tests based upon synthetic peptides corresponding to specific from human immnodeficiency viruses confirm their ability to discriminate antibodies directed against both viruses in 42/47 samples (89.4%) ; in 5/47 (10.6%) this test could not distinguish double infection from cross-reactivity.

    Mots-clés Pascal : SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Virus HIV2, Epidémiologie, Incidence, Anticorps, Homme, Zaïre, Afrique, Sérum, Exploration immunologique, Réaction croisée, Infection mixte, Facteur risque, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, HIV-2 virus, Epidemiology, Incidence, Antibody, Human, Zaire, Africa, Serum, Immunological investigation, Cross reaction, Mixed infection, Risk factor, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0569727

    Code Inist : 002B06D01. Création : 09/06/1995.