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  1. Leukocyte reduction of cellular blood components : effectiveness, benefits, quality control, and costs.

    Article, Communication - En anglais

    College of American Pathologists. Conference. USA, 1993/08/24.

    Cellular blood components contain passenger donor leukocytes.

    Transfusion of passenger leukocytes may be associated with alloimmunization to leukocyte antigens, febrile transfusion reactions, refractoriness to platelet transfusion, severe pulmonary dysfunction, graft-vs-host disease, the transmission of infectious diseases, and immune modulation.

    Advanced leukocyte-reduction filters enable the removal of up to 99.9% of leukocytes from cellular blood components.

    Clinical trials suggest that the use of leukocyte-reduction filters may prevent or diminish the probability of febrile transfusion reactions, alloimmunization, and cytomegalovirus infection, but controversy exists regarding the effectiveness of leukocyte reduction in preventing immune modulation.

    Mots-clés Pascal : Transfusion, Sang, Constituant sang, Filtrage, Leucocyte, Contrôle qualité, Coût, Analyse avantage coût, Complication, Article synthèse

    Mots-clés Pascal anglais : Transfusion, Blood, Blood product, Filtering, Leukocyte, Quality control, Costs, Cost benefit analysis, Complication, Review

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0563846

    Code Inist : 002B27D01. Création : 09/06/1995.