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  1. Involvement of immunologic mechanisms in a guinea pig model of Western red cedar asthma.

    Article - En anglais

    Western red cedar asthma is the most common form of occupational asthma in the Pacific Northwest.

    Plicatic acid (PA) is the chemical component of Western red cedar that causes asthma.

    The role of immunologic processes involved in the PA-induced asthmatic reaction has not been established.

    To characterize the machanisms of PA-induced asthmatic reaction, guinea pigs were sensitized to PA through biweekly injection of PA-ovalbumin conjugate with aluminium hydroxide as an adjuvant for a period of 6 months.

    Mots-clés Pascal : Asthme, Etiologie, Allergie, Immunité humorale, Histamine, Prostaglandine D2, IgG1, Pathogénie, Modèle animal, Porc, Artiodactyla, Ungulata, Mammalia, Vertebrata, Animal, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Maladie professionnelle, Médecine travail, Immunopathologie, Arachidonique acide dérivé, Cèdre rouge, Plicatique acide

    Mots-clés Pascal anglais : Asthma, Etiology, Allergy, Humoral immunity, Histamine, Prostaglandin D2, IgG1, Pathogenesis, Animal model, Pig, Artiodactyla, Ungulata, Mammalia, Vertebrata, Animal, Respiratory disease, Obstructive pulmonary disease, Occupational disease, Occupational medicine, Immunopathology, Arachidonic acid derivatives

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0562197

    Code Inist : 002B06C02. Création : 09/06/1995.