Cuzick and Edwards (JR Stat Soc [B] 1990 ; 52 : 73-104) have proposed a case-control test to detect spatial clustering.
The test statistic is the sum, over all cases, of the number of each case's k nearest neighbors that also are cases.
Their approach is attractive in that it accounts for geographic variation in population density and because it allows one to account for confounders, both known and unknown, through the judicious selection of controls.
However, the test assumes case locations are known exactly, when, in practice, case locations are usually approximated by the centers of areas such as census tracts and zip code zones.
In such situations, « ties » arise when cases and controls are assigned to the same area, and the loss of information precludes calculation of the test statistic.
Mots-clés Pascal : Epidémiologie, Méthodologie, Espace temps, Analyse amas, Analyse statistique
Mots-clés Pascal anglais : Epidemiology, Methodology, Space time, Cluster analysis, Statistical analysis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0556136
Code Inist : 002B30A01A1. Création : 09/06/1995.