With the use of two different approaches to study multiple primaries in anal cancer patients, the authors sought clues to the etiology of anal cancer.
Based on data from the Danish Cancer Registry for 1943-1989, previous cancers in 831 anal cancer patients were compared with cancers in 12,376 matched population controls, and subsequent cancers in 955 anal cancer patients were compared with expected numbers based on population rates.
Overall, previous cancers were in excess among anal cancer patients (odds ratio (OR)=1.7,95% confidence interval (Cl) 1.3-2.1).
Elevated risks were observed especially for the vulva/vagina (OR=15.4,95% CI 4.9-48.0), cervix (OR=4.3,95% CI 2.7-6.9), and lymphoma/leukemia (OR=3.9,95% CI 1.5-10.4).
Mots-clés Pascal : Tumeur maligne, Anus, Epidémiologie, Facteur risque, Danemark, Europe, Etiologie, Association, Second cancer, Homme
Mots-clés Pascal anglais : Malignant tumor, Anus, Epidemiology, Risk factor, Denmark, Europe, Etiology, Association, Second cancer, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0556131
Code Inist : 002B13B01. Création : 09/06/1995.