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  1. Does early physical maturity influence breast cancer risk ?

    Article - En anglais

    Earlier onset of menarche and tallness in adult women are mainly confirmed as risk markers for breast cancer.

    Recent disparate case-control studies have reported abdominal-type obesity and higher circulating levels of insulin, testosterone and insulin-like growth factor 1, to be further risk markers for breast cancer.

    There is evidence that abdominal-type obesity is recognisable in girls even before puberty, and disparate studies have shown it to be correlated with earlier onset of menarche, insulin resistance leading to hyperinsulinaemia, and an abnormal sex steroid profile.

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Puberté précoce, Obésité, Hyperinsulinémie, Hormone stéroïde sexuelle, Taille corporelle, Epidémiologie, Monde Ouest, Adulte, Homme, Glande mammaire pathologie, Endocrinopathie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Precocious puberty, Obesity, Hyperinsulinemia, Sex steroid hormone, Body size, Epidemiology, Western countries, Adult, Human, Mammary gland diseases, Endocrinopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0542806

    Code Inist : 002B20E02. Création : 199501.