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  1. Protection provided by Haemophilus influenzae type b conjugate vaccines in Los Angeles County : a case-control study.

    Article - En anglais

    The objective was to assess the degree of disease control and to evaluate the protective efficacy of licensed Haemophilus influenzae type b (Hib) conjugate vaccines (HbOC, PRP-OMP, PRP-D) used routinely in children 2 to 35 months of age.

    We conducted a case-control study in Los Angeles County between January 1,1991, and December 31,1992, and a cohort analysis of Hib cases between 1983 and 1992.

    For the case-control study 105 cases of invasive Hib disease were identified and 767 geographically and age-matched controls were selected by random digit telephone dialing.

    Sixteen HbOC vaccine failures occurred>14 days after a single dose of vaccine, 6 vaccine failures after 2 doses and 3 failures after 3 doses ; 2 cases occurred 6 and 12 days, respectively, after an initial dose of HbOC.

    Mots-clés Pascal : Haemophilus influenzae, Pasteurellaceae, Bactérie, Enfant, Homme, Calendrier vaccination, Vaccination, Immunoprophylaxie, Protection, Vaccin associé, Etude cas

    Mots-clés Pascal anglais : Haemophilus influenzae, Pasteurellaceae, Bacteria, Child, Human, Vaccination schedule, Vaccination, Immunoprophylaxis, Protection, Mixed vaccine, Case study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0535566

    Code Inist : 002B05B02E. Création : 199501.