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  1. Risk of benzene-induced leukemia : a sensitivity analysis of the pliofilm cohort with additional follow-up and new exposure estimates.

    Article - En anglais

    This report updates the risk assessment by Crump and Allen (1984) or benzene-induced leukemia that was used by OSHA (1987) to support its reduction of the permissible exposure limit (PEL) to 1 ppm and that also was the basis for EPA's (1985) interim « unit risk » for benzene.

    The present study derives new risk estimates using data from follow-up through 1987 (whereas the earlier assessment only had follow-up available through 1978), and using new exposure estimates for this cohort developed by Paustenbach et al. (1992) that account for a number of factors that were unknwon or not fully evaluated in earlier exposure assessments.

    Mots-clés Pascal : Benzène, Carcinogène, Risque, Leucémie, Homme, Toxicité, Etude longitudinale, Epidémiologie, Etude cohorte, Exposition professionnelle, Médecine travail, Evaluation, Hémopathie maligne

    Mots-clés Pascal anglais : Benzene, Carcinogen, Risk, Leukemia, Human, Toxicity, Follow up study, Epidemiology, Cohort study, Occupational exposure, Occupational medicine, Evaluation, Malignant hemopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0513275

    Code Inist : 002B19B. Création : 199501.