This report updates the risk assessment by Crump and Allen (1984) or benzene-induced leukemia that was used by OSHA (1987) to support its reduction of the permissible exposure limit (PEL) to 1 ppm and that also was the basis for EPA's (1985) interim « unit risk » for benzene.
The present study derives new risk estimates using data from follow-up through 1987 (whereas the earlier assessment only had follow-up available through 1978), and using new exposure estimates for this cohort developed by Paustenbach et al. (1992) that account for a number of factors that were unknwon or not fully evaluated in earlier exposure assessments.
Mots-clés Pascal : Benzène, Carcinogène, Risque, Leucémie, Homme, Toxicité, Etude longitudinale, Epidémiologie, Etude cohorte, Exposition professionnelle, Médecine travail, Evaluation, Hémopathie maligne
Mots-clés Pascal anglais : Benzene, Carcinogen, Risk, Leukemia, Human, Toxicity, Follow up study, Epidemiology, Cohort study, Occupational exposure, Occupational medicine, Evaluation, Malignant hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0513275
Code Inist : 002B19B. Création : 199501.