This review aims at discussing the questions raised by the hydrocarbon-related chronic nephropathy and its possible consequence, the hydrocarbon-related chronic renal failure.
It has been attempted to adopt the point of view of the clinician.
Therefore, the most important part of the review is devoted to a presentation and an analysis of the available data on humans.
The main features of the available studies on human subjects are presented, their conclusions discussed in the light of the possible methodological flaws, and practical conclusions drawn.
After a discussion of the main difficulties encountered for selecting the suitable exposure indicator, the studies are discussed in order of decreasing quality of the study design (cohort, case-control, cross-sectional studies, and the case reports).
Mots-clés Pascal : Composé aromatique polycyclique, Toxicité, Hydrocarbure, Solvant organique, Appareil urinaire pathologie, Chronique, Exposition professionnelle, Homme, Médecine travail, Article synthèse, Epidémiologie, Rein, Suisse, Europe, Insuffisance rénale, Néphropathie glomérulaire
Mots-clés Pascal anglais : Polycyclic aromatic compound, Toxicity, Hydrocarbon, Organic solvent, Urinary system disease, Chronic, Occupational exposure, Human, Occupational medicine, Review, Epidemiology, Kidney, Switzerland, Europe, Renal failure, Glomerulonephritis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0506907
Code Inist : 002B03L06. Création : 199501.