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  1. The European atherosclerosis research study (EARS) : design and objectives.

    Article - En anglais

    The European Atherosclerosis Research Study-EARS-is a multicentre collaborative project sponsored by the European Community.

    Its main objective is to study, in young people, the biological expression of a paternal history of premature acute myocardial infarction (AMI) and the relative share of heredity and environment in this expression.

    In 14 centres in 11 European countries, the offspring of fathers who suffered from a documented AMI before the age of 55 years (cases) are compared with age-and sex-matched control individuals.

    Genetic variables (restriction fragment length polymorphisms of candidate genes), lifestyle variables and biochemical variables that are known or suspected to play a role in the development of coronary heart disease (CHD), are studied.

    Mots-clés Pascal : Infarctus, Myocarde, Epidémiologie, Adulte jeune, Homme, Antécédent, Parent, Déterminisme génétique, Mode de vie, Facteur risque, Etude comparative, Europe, Histoire familiale, Cardiopathie coronaire, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Infarct, Myocardium, Epidemiology, Young adult, Human, Antecedent, Parent, Genetic inheritance, Life habit, Risk factor, Comparative study, Europe, Family story, Coronary heart disease, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0504124

    Code Inist : 002B12A03. Création : 199501.