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  1. Proposal protocols for the determination of potential ocular effects of organophosphorus pesticides.

    Article, Communication - En anglais

    Symposium on ocular effect of organophosphate exposure. Bethesda MD USA, 1992/06/04.

    The US Environmental Protection Agency now requires ocular toxicity testing to support the registration of organophosphorus pesticides.

    As a first step toward guideline development for the conduct of these studies, preliminary protocols for ocular toxicity testing in the non-rodent and rodent are being proposed by the Office of Pesticide Programs.

    Proposed protocol parameters include determination of animal health status, measurement of plasma, erythrocyte and retinal cholinesterase activities, ocular assessment by routine ophthalmological examination, slit lamp biomicroscopy, fundic observations, tonometry, electroretinography and determination of objective refractivity, pupillary response and tracking.

    Mots-clés Pascal : Pesticide, Organophosphoré, Insecticide, Toxicité, Animal, Evaluation, Essai, Législation, Recommandation, Etats Unis, Amérique du Nord, Amérique, Homme, Oeil pathologie

    Mots-clés Pascal anglais : Pesticides, Organophosphorus compounds, Insecticide, Toxicity, Animal, Evaluation, Test, Legislation, Recommendation, United States, North America, America, Human, Eye disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0494921

    Code Inist : 002B03G. Création : 199501.