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  1. Molecular epidemiology of HIV-1 in the former Soviet Union : analysis and env V3 sequences and their correlation with epidemiologic data.

    Article - En anglais

    Objective 

    To investigate the HIV-1 V3 sequence diversity in the former Soviet Union in 30 subjects infected with HIV-1 via different modes of transmission.

    Patients 

    A cohort of children infected after exposure to nonsterile needles during the epidemic in 1988-1989 in southern Russia (Elista, n=12 and Rostov-on-Don, n=10), and eight HIV-seropositive subjects from Belarus (Minsk), infected via sexual (n=7) and parenteral (n=1) infection.

    Methods 

    The HIV-1 V3 encoding region was amplified by nested polymerase chain reaction on DNA of primary peripheral blood mononuclear cells collected from the study subjects and then cloned and sequenced.

    Mots-clés Pascal : SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Variabilité génétique, Séquence nucléotide, DNA, Enfant, Homme, Epidémiologie, Biologie moléculaire, Russie, Eurasie, Transmission, Mode transmission, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Genetic variability, Nucleotide sequence, DNA, Child, Human, Epidemiology, Molecular biology, Russia, Eurasia, Transmission, Transmission mode, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0480404

    Code Inist : 002B06D01. Création : 199501.