We have investigated the relationship between annual decline in forced expiratory volume in one second (deltaFEV1) and bronchial responsiveness (BR) in aluminium potroom workers.
BR was measured in a cross-sectional study of 337 aluminium potroom workers half-way through a 6 yr follow-up study of lung function.
A skin-prick test (SPT) was also performed.
During follow-up the mean number of measurements of lung function (FEV1) in each subject was 6.8. Mean deltaFEV1 was 21.3 ml. yr-1 (within subject SD=30.5 ml. yr-1).
Mean deltaFEV, was 57.0,44.5 and 16.6 ml. yr-1 in subjects who had provocative concentration producing a 20% fall in FEV1 (PC20) ¾8.0,8.1-32.0 and>32.0 mg. ml-1, respectively.
Mots-clés Pascal : Exposition professionnelle, Aluminium, Homme, Epidémiologie, Hyperréactivité, Bronche, VEMS, Pronostic, Test provocation, Médecine travail
Mots-clés Pascal anglais : Occupational exposure, Aluminium, Human, Epidemiology, Hyperreactivity, Bronchus, Maximal expiratory volume per second, Prognosis, Provocation test, Occupational medicine
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0470413
Code Inist : 002B11B. Création : 199501.