Bronchial responsiveness and decline in FEV1 iin aluminium potroom workers.
We have investigated the relationship between annual decline in forced expiratory volume in one second (deltaFEV1) and bronchial responsiveness (BR) in aluminium potroom workers.
BR was measured in a cross-sectional study of 337 aluminium potroom workers half-way through a 6 yr follow-up study of lung function.
A skin-prick test (SPT) was also performed.
During follow-up the mean number of measurements of lung function (FEV1) in each subject was 6.8. Mean deltaFEV1 was 21.3 ml. yr-1 (within subject SD=30.5 ml. yr-1).
Mean deltaFEV, was 57.0,44.5 and 16.6 ml. yr-1 in subjects who had provocative concentration producing a 20% fall in FEV1 (PC20) ¾8.0,8.1-32.0 and>32.0 mg. ml-1, respectively.
Mots-clés Pascal : Exposition professionnelle, Aluminium, Homme, Epidémiologie, Hyperréactivité, Bronche, VEMS, Pronostic, Test provocation, Médecine travail
Mots-clés Pascal anglais : Occupational exposure, Aluminium, Human, Epidemiology, Hyperreactivity, Bronchus, Maximal expiratory volume per second, Prognosis, Provocation test, Occupational medicine
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0470413
Code Inist : 002B11B. Création : 199501.