A modification of the model of Pike et al. (Nature 1983 ; 303 : 767-70) was applied to 91,523 women in the Nurses'Health Study who did not report prevalent cancer initially and who were followed for 14 years (1,212,855 person-years and 2,341 incident breast cancers).
The model took into account current age, age at all births, age at menopause, and age at menarche in predicting the annual and cumulative incidence of breast cancer.
The authors found that ages both at first birth and at subsequent births have long-term influence on breast cancer incidence.
The incidence density for parous women was greater than for nulliparous women for 20-30 years after the time of the first birth.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Epidémiologie, Etude longitudinale, Incidence, Facteur risque, Reproduction, Modèle statistique, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Epidemiology, Follow up study, Incidence, Risk factor, Reproduction, Statistical model, Human, Female, United States, North America, America, Mammary gland diseases
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0467485
Code Inist : 002B20E02. Création : 199501.