Two acellular pertussis vaccines combined with diphtheria and tetanus toxoids (APDT vaccines) were compared with a whole cell PDT (WCPDT) vaccine in primary immunization in Ghana.
One is a liquid vaccine which is used for general immunization in Japan and the other is a freeze-dried vaccine newly developed as a heat-stable vaccine.
Eighty-nine infants were recruited in the study.
Sixtyeight who completed three doses of the immunization were assessed for immunological responses.
Twentyone dropped out because of sickness or moving from the study area.
A total of 242 vaccinations in 89 infants were followed up for adverse reactions.
Mots-clés Pascal : Vaccination, Vaccin, Ghana, Afrique, Coqueluche, Bactériose, Infection, Diphtérie, Tétanos, Efficacité, Etude comparative, Japon, Asie, Vaccin acellulaire
Mots-clés Pascal anglais : Vaccination, Vaccine, Ghana, Africa, Whooping cough, Bacteriosis, Infection, Diphtheria, Tetanus, Efficiency, Comparative study, Japan, Asia, Acellular vaccine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0459447
Code Inist : 002B05A02. Création : 199406.