Early studies suggested that gastric surgery for benign ulcer disease was associated with a subsequent increase in the risk of large bowel cancer.
Dietary fats, altered bacterial flora, and secondary bile acids are considered to play a major role in the disease etiology.
Gastric surgery is known to alter bile salt metabolism as well as bacterial flora in the colon.
This cohort study was designed to investigate the risk of large bowel cancer following gastric surgery for benign ulcer disease and to identify potential patient and treatment characteristics that may be associated with this risk.
A cohort of 15,983 males was selected from Department of Veterans Affairs hospital admissions in 1970 and 1971.
Mots-clés Pascal : Tumeur maligne, Intestin, Epidémiologie, Ulcère, Estomac, Chirurgie, Traitement, Homme, Mâle, Etude cohorte, Etats Unis, Amérique du Nord, Amérique, Intestin pathologie, Appareil digestif pathologie
Mots-clés Pascal anglais : Malignant tumor, Gut, Epidemiology, Ulcer, Stomach, Surgery, Treatment, Human, Male, Cohort study, United States, North America, America, Intestinal disease, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0457503
Code Inist : 002B13B01. Création : 199406.