A case-control study of oral contraceptive use and invasive epithelial ovarian cancer.
The relation of oral contraceptive use to the risk of ovarian cancer was assessed with data collected during 1977-1991 from patients under 65 years of age in hospitals in Boston, New York, Philadelphia, and Baltimore.
We compared 441 women with recently diagnosed invasive epithelial ovarian cancer to 2,065 control women.
Logistic regression was used to control risk factors for ovarian cancer.
The multivariate relative risk estimate decreased with the increasing duration of oral contraceptive use (p<0.05): the estimate was close to 1.0 for duration categories of less than 3 years; it was reduced for the categories of 3-4 years of use and greater, but it did not decline further as the duration of use increased.
Mots-clés Pascal : Tumeur maligne, Ovaire, Epidémiologie, Contraceptif, Voie orale, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Ovaire pathologie, Appareil génital femelle pathologie
Mots-clés Pascal anglais : Malignant tumor, Ovary, Epidemiology, Contraceptive, Oral administration, Human, Female, United States, North America, America, Ovarian diseases, Female genital diseases
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0457500
Code Inist : 002B20C02. Création : 199406.