Sampling of radical prostatectomy specimens : how much is adequate ?
Prostate glands from 52 patients with clinical stage B carcinoma were examined using two sampling techniques.
After fixation and conization of the apical portions, each gland was serially sectioned with sections mounted whole on oversized glass slides and examined for pathologic features of prognostic importance.
A second examination was subsequently conducted on the same tissue using only alternate sections.
No differences in tumor type, grade, Gleason score, multiplicity, or capsular penetration were detected in 75% of cases.
The discrepancies that did occur were most often minor variations in multiplicity and Gleason score.
Of the 20 glands with capsular penetration observed with the serial sectioning method, 17 (85%) were detected using alternate sectioning.
Mots-clés Pascal : Appareil génital pathologie, Appareil génital mâle pathologie, Appareil urinaire pathologie, Economie santé, Tumeur maligne, Pronostic, Technique, Homme, Etude comparative, Anatomopathologie, Chirurgie, Prostate pathologie, Epithélioma, Prostate, Echantillonnage, Prostatectomie
Mots-clés Pascal anglais : Genital diseases, Male genital diseases, Urinary system disease, Health economy, Malignant tumor, Prognosis, Technique, Human, Comparative study, Pathology, Surgery, Prostatic disease, Carcinoma, Prostate, Sampling, Prostatectomy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0455505
Code Inist : 002B14D02. Création : 199406.