Diabetic cardiomyopathy as a distinct entity was first recognized by Rubler et al. in diabetics with congestive heart failure (CHF), who had no evidence of coronary atherosclerosis.
The Framingham study showed a 2.4-fold increased incidence of CHF in diabetic men and a 5.1-fold increase in diabetic women over 18 years.
Pathological studies show left ventricular hypertrophy and fibrosis with varying degrees of small vessel disease, the functional significance of which is uncertain.
Hypertension was recognized as an important cofactor in the development of fatal congestive heart failure in diabetics.
On cardiac catheterization, in patients symptomatic of heart failure, either congestive or restrictive patterns have been observed.
Mots-clés Pascal : Diabète, Insuffisance cardiaque, Physiopathologie, Complication, Homme, Facteur risque, Epidémiologie, Chien, Fissipedia, Carnivora, Mammalia, Vertebrata, Rat, Rodentia, Animal, Endocrinopathie, Appareil circulatoire pathologie, Cardiopathie
Mots-clés Pascal anglais : Diabetes mellitus, Heart failure, Pathophysiology, Complication, Human, Risk factor, Epidemiology, Dog, Fissipedia, Carnivora, Mammalia, Vertebrata, Rat, Rodentia, Animal, Endocrinopathy, Cardiovascular disease, Heart disease
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0447395
Code Inist : 002B21E01B. Création : 199406.