During the period 1981-1986, 1605 infants presenting a major congenital heart defect (CHD) were identified in Sweden.
Using the personal identification numbers of the mothers, 1507 of them could be linked to the Medical Birth Registry and two controls were selected for each infant.
For this total of 4521 infants, 2686 postoccurrence sibs bom during the period 1981-1989 were identified from the Medical Birth Registry.
The tendency to have one or more sibs was higher among cases than among controls and was correlated to the life status of the proband.
This tendency did not vary according to the type of CHD when controlling for life status.
The prevalence at birth of CHD was almost four times higher among sibs of CHD infants than among sibs of normal infants.
Mots-clés Pascal : Cardiopathie, Congénital, Homme, Suède, Europe, Récurrence, Epidémiologie, Appareil circulatoire pathologie, Maladie congénitale
Mots-clés Pascal anglais : Heart disease, Congenital, Human, Sweden, Europe, Recurrence, Epidemiology, Cardiovascular disease, Congenital disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0439676
Code Inist : 002B12A08. Création : 199406.