A small rural district in the most northerly province of Sweden was found to have a very high occurrence of multiple sclerosis.
A total of 12 patients with multiple sclerosis among 4744 inhabitants were identified (five females, seven males), corresponding to a prevalence of 253/100 000.
Many of the patients were related and a further 21 cases with multiple sclerosis (14 females, seven males), mostly living in the neighbouring area, have family ties to the district.
A genealogical investigation showed that 22 of the 33 patients identified had ties of kinship and thus, to our knowledge, the largest aggregation of multiple sclerosis in a family is presented.
Mots-clés Pascal : Sclérose en plaque, Système nerveux pathologie, Epidémiologie, Homme, Etude familiale, Suède, Europe
Mots-clés Pascal anglais : Multiple sclerosis, Nervous system diseases, Epidemiology, Human, Family study, Sweden, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0416458
Code Inist : 002B17F. Création : 199406.