Varicella-zoster virus (VZV) is a highly contagious infectious agent that causes outbreaks in institutional settings.
Transmission of VZV is felt to occur following direct contact with an infected individual and by aerosol spread.
To document the aerosolization of VZV, a polymerase chain reaction (PCR) assay was used to detect VZV DNA in air samples obtained from hospital rooms of patients with active VZV infection.
VZV DNA was detected in 64 (82%) of 78 air samples from rooms housing patients with active varicella and 9 (70%) of 13 samples from rooms of patients with herpes zoster.
VZV was detected 1.2-5.5 m from patients'beds and for 1-6 days following onset of rash.
On some occasions, VZV DNA could be detected outside the hospital isolation rooms housing patients.
Mots-clés Pascal : Varicelle, Virose, Infection, Virus varicelle, Alphaherpesvirinae, Herpesviridae, Virus, Milieu ambiant, Zona, Exploration microbiologique, Epidémiologie, Transmission homme homme, Homme, Réaction chaîne polymérase, Air, DNA, Hôpital, Isolement, Hygiène, Peau pathologie, Système nerveux pathologie
Mots-clés Pascal anglais : Varicella, Viral disease, Infection, Varicella zoster virus, Alphaherpesvirinae, Herpesviridae, Virus, Ambient medium, Herpes zoster, Microbiological investigation, Epidemiology, Transmission from man to man, Human, Polymerase chain reaction, Air, DNA, Hospital, Isolation, Hygiene, Skin disease, Nervous system diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0345778
Code Inist : 002B05C02B. Création : 199406.