Molecular epidemiological studies of human herpesvirus 6 in families.
The mode of transmission of human herpesvirus 6 (HHV-6) was investigated by molecular epidemiological techniques in four families.
HHV-6 was isolated from the peripheral blood of seven infants with exanthem subitum, including siblings, and from the saliva of two mothers.
These isolates were examined for genetic relatedness by means of restriction enzymes analysis of purified DNA.
While the profiles of the digestion patterns differed among families, they were very similar in a particular family.
These results may suggest that HHV-6 is transmitted primarily from mother to child.
Mots-clés Pascal : Herpesvirus hominis 6, Herpesviridae, Virus, Transmission homme homme, Nourrisson, Homme, Mère, Exanthème subit, Virose, Infection, Epidémiologie moléculaire, Peau pathologie
Mots-clés Pascal anglais : Herpesvirus hominis 6, Herpesviridae, Virus, Transmission from man to man, Infant, Human, Mother, Exanthema subitum, Viral disease, Infection, Molecular epidemiology, Skin disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0342960
Code Inist : 002A05C06. Création : 199406.