Mortality to January 1, 1991, has been studied in 2,067 women in Scotland given X-ray therapy for metropathia haemorrhagica during the period 1940-1960.
Average follow-up was 28 years.
Overall, 1,313 deaths were observed compared with 1,297.01 expected from Scottish rates [standardized mortality ratio (SMR): 1.01]. Mortality was increased for cancers of heavily irradiated pelvic sites (SMR 5+ years after irradiation: 1.46) following mean doses to organs in the vicinity of the pelvis in the range 2.6-5.3 Gy.
For these cancers the SMR was higher 30+ years after irradiation than at 5-29 years, indicating that the effects of exposure last for over 30 years, and in this period bladder cancer mortality was exceptionally high (SMR=4.91).
Mots-clés Pascal : Hémorragie, Utérus, Essentiel, Radiothérapie, Mortalité, Epidémiologie, Etude cohorte, Etats Unis, Amérique du Nord, Amérique, Homme, Utérus pathologie, Appareil génital femelle pathologie, Traitement, Métropathie hémorragique
Mots-clés Pascal anglais : Hemorrhage, Uterus, Essential, Radiotherapy, Mortality, Epidemiology, Cohort study, United States, North America, America, Human, Uterine diseases, Female genital diseases, Treatment
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0318840
Code Inist : 002B26L. Création : 199406.