Serum micronutrients in relation to pre-cancerous gastric lesions.
Serum levels of retinol, beta-carotene, ascorbic acid, alpha-tocopherol, selenium, ferritin, copper, and zinc were assayed for approximately 600 adults aged 35 to 64 with pre-cancerous gastric lesions in an area of China with one of the world's highest rates of stomach cancer.
Previous studies have shown that the cancers generally are preceded by chronic atropic gastritis (CAG), intestinal metaplasia (IM) and dysplasia.
Concentrations of beta-carotene and ascorbic acid were significantly lower among individuals with IM than among those whose most severe lesion was superficial gastritis or CAG.
The associations with IM for these nutrients were strong and independent.
Mots-clés Pascal : Tumeur maligne, Estomac, Facteur risque, Lésion précancéreuse, Micronutriment, Sérum, Ascorbique acide, Carotène, Rétinol, Sélénium, Tocophérol, Epidémiologie, Ferritine, Cuivre, Zinc, Chine, Asie, Homme, Estomac pathologie, Appareil digestif pathologie, Vitamine, Oligoélément, Ferroprotéine
Mots-clés Pascal anglais : Malignant tumor, Stomach, Risk factor, Premalignant lesion, Micronutrient, Serum, Ascorbic acid, Carotene, Retinol, Selenium, Tocopherol, Epidemiology, Ferritin, Copper, Zinc, China, Asia, Human, Gastric disease, Digestive diseases, Vitamin, Oligoelement, Ferroprotein
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0311924
Code Inist : 002B13B01. Création : 199406.