Increasing interest has been focused on DNA ploidy, hormone receptor status and tumour size as prognostic factors in node-negative breast cancer.
We analysed these factors in patients operated on for primary invasive breast cancer between January 1981 and December 1987 in a prospective study of 248 women with no involved axillary nodes and 188 women with positive nodes followed until 15 April 1989.
Oestrogen or progesterone receptor negativity, aneuploidy and tumour diameter exceeding 20 mm were studied as negative prognostic signs in life table analyses and Cox proportional hazards models of corrected survival.
Corrected survival decreased with increasing number of negative signs.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, DNA, Ploïdie, Récepteur hormonal, Taille, Mortalité, Epidémiologie, Suède, Europe, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, DNA, Ploidy, Hormonal receptor, Size, Mortality, Epidemiology, Sweden, Europe, Human, Mammary gland diseases
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0291360
Code Inist : 002B20E02. Création : 199406.