Epidemiologic studies of men consistently demonstrate a positive association between tobacco smoking and risk of colorectal adenomas, precursors of cancer, but have not consistently shown an association between smoking and colorectal cancer.
We hypothesized that smoking acts as an initiator of colorectal neoplasia and that the association with cancer has been obscured because the time is long between onset of smoking and diagnosis of cancer.
Our purpose was to examine the association between cigarette smoking and risk of colorectal adenoma and colorectal cancer in men and to estimate the minimum induction period between the start of smoking and the diagnosis of cancer.
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Adénome, Facteur risque, Tabagisme, Etude longitudinale, Prospective, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Mâle, Homme, Côlon pathologie, Rectum pathologie, Intestin pathologie, Appareil digestif pathologie, Tumeur bénigne
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Adenoma, Risk factor, Tobacco smoking, Follow up study, Prospective, Epidemiology, United States, North America, America, Male, Human, Colonic disease, Rectal disease, Intestinal disease, Digestive diseases, Benign neoplasm
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0289713
Code Inist : 002B13B01. Création : 199406.