Immunoglobulin levels and cellular immune function in lead exposed workers.
The immunological status of lead acid battery workers with blood lead levels and urinary delta- aminolevulinic acid (ALA-U) concentrations ranging from safe to toxic levels has been examined and compared with those of non-exposed, age and sex matched controls.
No differences in the serum concentrations of IgG, IgA and IgM between the populations were observed and there existed no correlation between blood lead level or ALA-U concentrations and serum immunoglobulin levels.
In addition assessment was made of the capacity of peripheral blood mononuclear cells to respond to the mitogen phytohaemagglutinin (PHA), a correlate of T cell function.
Mots-clés Pascal : Plomb, Métal lourd, Exposition professionnelle, Homme, Toxicité, Immunodépression, Exploration immunologique, Immunité humorale, Immunoglobuline, Lymphocyte T, Immunité cellulaire, Médecine travail, Immunopathologie
Mots-clés Pascal anglais : Lead, Heavy metal, Occupational exposure, Human, Toxicity, Immunosuppression, Immunological investigation, Humoral immunity, Immunoglobulins, T-Lymphocyte, Cellular immunity, Occupational medicine, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0263467
Code Inist : 002B03L05. Création : 199406.